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Evidence

Control group

Also known as: comparison group

The group used as a comparison when assessing an intervention in a study.

Source-checked educational compilation · Not independently clinically reviewed

What this means in a clinic conversation

A comparator may be usual care, another treatment or a placebo. Improvement within the treatment group answers a different question from improvement relative to the control group.

A question to bring

What did the comparison group receive, and how did the groups differ at follow-up?

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Related and commonly confused terms

Use the term in context

Sources and editorial context

This definition was compiled from the sources below and has not received independent clinical review. It supports understanding and consultation preparation.

  1. NCI Dictionary: control group · National Cancer InstituteReference checked 2026-10-02
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